首页|不同强度的抗阻运动对肺癌伴癌因性疲乏患者内分泌激素的调节作用

不同强度的抗阻运动对肺癌伴癌因性疲乏患者内分泌激素的调节作用

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目的 探讨不同强度的抗阻运动对肺癌伴癌因性疲乏(CRF)患者内分泌激素的调节作用.方法 选择 2020 年 1 月至 2023 年 10 月于医院就诊的 90 例肺癌伴CRF患者为研究对象,采用随机数字表法分为试验组和对照组,每组 45 例.试验组予 60%肌肉一次最大重复负荷(1-RM)抗阻运动,对照组予 40%1-RM抗阻运动,两组均进行 8 周抗阻运动.比较两组治疗前及治疗 8 周后血清甲状腺激素[三碘甲状腺原氨酸(T3)和四碘甲状腺原氨酸(T4)]和皮质醇(Cor)水平、疲乏症状(MFSI-SF)及临床疗效.结果 治疗8周后,两组血清T3、T4 和Cor水平均高于治疗前,且试验组高于对照组,差异有统计学意义(P<0.05);两组MFSI-SF评分均低于治疗前,且试验组低于对照组,差异有统计学意义(P<0.05);试验组临床总有效率高于对照组,差异有统计学意义(P<0.05).结论 不同强度的抗阻运动均可在一定程度上调整肺癌伴CRF患者内分泌激素、疲乏症状,具有较好的临床疗效,其中 60%1-RM的抗阻运动改善效果更明显.
The Regulatory Effect of Different Intensities of Resistance Exercise on Endocrine Hormones in Lung Cancer Patients with Cancer-Related Fatigue
Objective To explore the regulatory effect of different intensities of resistance exercise on endocrine hormones in patients with cancer-related fatigue(CRF)in lung cancer.Methods Ninety lung cancer patients with CRF who visited hospitals from January 2020 to October 2023 were selected as the study subjects.They were randomly divided into an experimental group and a control group using a random number table method,with 45 cases in each group.The experimental group received resistance exercise with a maximum repetitive load(1-RM)of 60% of the muscles,while the control group received resistance exercise with 40% of the muscles.The changes in serum thyroid hormone(T3 and T4)and cortisol(Cor)levels and fatigue symptoms(MFSI-SF)before and after treatment between two groups,as well as the clinical efficacy of the two groups were compared.Results After 8 weeks of treatment,the serum levels of T3,T4,and Cor in the two groups were higher than before treatment,and the experimental group was higher than the control group,with statistical significance(P<0.05);The MFSI SF scores of the two groups were lower than before treatment,and the experimental group was lower than the control group,with a statistically significant difference(P<0.05);The total clinical effective rate of the experimental group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusions Resistance exercises of different intensities can to some extent adjust endocrine hormones and fatigue in lung cancer patients with CRF It has clinical efficacy,with 60% of 1-RM showing more significant improvement in resistance exercise.

Lung cancerCancer induced fatigueResistance movementEndocrine hormones

许海阳、孙巧丹、卢红阳

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浙江省台州医院 (浙江台州 317000)

肺癌 癌因性疲乏 抗阻运动 内分泌激素

2024

医疗装备
国家食品药品监督管理局北京医疗器械质量监督检验中心 北京市医疗器械检验所

医疗装备

影响因子:0.339
ISSN:1002-2376
年,卷(期):2024.37(12)
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