The Regulatory Effect of Different Intensities of Resistance Exercise on Endocrine Hormones in Lung Cancer Patients with Cancer-Related Fatigue
Objective To explore the regulatory effect of different intensities of resistance exercise on endocrine hormones in patients with cancer-related fatigue(CRF)in lung cancer.Methods Ninety lung cancer patients with CRF who visited hospitals from January 2020 to October 2023 were selected as the study subjects.They were randomly divided into an experimental group and a control group using a random number table method,with 45 cases in each group.The experimental group received resistance exercise with a maximum repetitive load(1-RM)of 60% of the muscles,while the control group received resistance exercise with 40% of the muscles.The changes in serum thyroid hormone(T3 and T4)and cortisol(Cor)levels and fatigue symptoms(MFSI-SF)before and after treatment between two groups,as well as the clinical efficacy of the two groups were compared.Results After 8 weeks of treatment,the serum levels of T3,T4,and Cor in the two groups were higher than before treatment,and the experimental group was higher than the control group,with statistical significance(P<0.05);The MFSI SF scores of the two groups were lower than before treatment,and the experimental group was lower than the control group,with a statistically significant difference(P<0.05);The total clinical effective rate of the experimental group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusions Resistance exercises of different intensities can to some extent adjust endocrine hormones and fatigue in lung cancer patients with CRF It has clinical efficacy,with 60% of 1-RM showing more significant improvement in resistance exercise.