The Effect of a Novel Fecal Bacteria Transplantation Filtration Device on the Treatment of Diarrhea Irritable Bowel Syndrome Patients Through Fecal Bacteria Transplantation
Objective To analyze the effectiveness of using a novel fecal bacteria transplantation filtration device to reconstruct the Intestinal flora in patients with diarrhea irritable bowel syndrome(IBS).Methods With the selection of 114 patients with diarrhea irritable bowel syndrome admitted to the hospital from January to July 2023 as the research subjects,according to the random number table method,they were divided into the control group(obtained fecal bacteria through conventional methods and transplanted)and the experimental group(obtained fecal bacteria using a new fecal bacteria transplantation filtration device and transplanted),with 57 cases in each group.The rectal volume stimulation sensory indicators(defecation,pain,sensory threshold),serum inflammatory indicators[interleukin-6(IL-6),tumor necrosis factor α(TNF-α),interferon-γ(IFN-γ)],serum functional indicators[vasoactive intestinal peptide(VIP),motilin(MTL),substance P(SP)],and distribution of intestinal flora(lactobacilli,bifidobacteria,enterococci)content in the fecal bacteria transplantation were compared between the two groups before and after 30 days of treatment.Results After 30 days of treatment,the defecation,pain and sensory thresholds of experimental group were higher than those of control group(P<0.05).The levels of IL-6,TNF-α,IFN-γ,VIP,MTL,and SP in the experimental group were significantly lower than those in the control group(P<0.05);The contents of lactobacillus and bifidobacteria in the experimental group were significantly higher than that in the control group,while the content of enterococcus was significantly lower than that in the control group(P<0.05).Conclusion The extraction and transplantation of fecal bacteria through the new fecal bacteria transplantation filter device has a good effect on the reconstruction of intestinal flora in patients with diarrhea irritable bowel syndrome,which improves the rectal volume stimulation sensation index,increases the content of intestinal flora,and reduces the content of serum inflammatory indicators and functional indicators.
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