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大动脉炎临床诊治研究进展

Research progress in diagnosis and treatment of Takayasu arteritis

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大动脉炎作为罕见疾病,是一种影响主动脉及其主要分支的慢性炎性疾病.其疾病特征包括血管狭窄、闭塞或动脉瘤,病因可能与自身免疫异常有关.该病临床表现多样,早期诊断具有挑战性,且可能导致严重并发症,如脑卒中、心脏瓣膜病等.诊断依赖影像学检查和实验室指标,治疗主要以糖皮质激素和免疫抑制剂为主,严重病例可能需要手术或血管内干预.中医药治疗具有潜力,尤其针灸疗法的免疫作用常被用于治疗该病,但仍需确切疗效证据.大动脉炎的管理挑战在于其疾病进展的不确定性和治疗的长期性,未来研究需致力于改善诊断、治疗方法和患者预后.文章对大动脉炎临床诊治研究进展作一综述.
Takayasu's arteritis,a rare disease,is a chronic inflammatory condition affecting the aorta and its main branches.Characterized by vascular narrowing,occlusion,or aneurysms,its etiology may be associated with autoimmune abnormalities.The disease presents with diverse clinical manifestations,making early diagnosis challenging and potentially leading to severe complications such as stroke and heart valve disease.Diagnosis relies on imaging studies and laboratory markers,with treatment primarily involving corticosteroids and immunosuppressants.Severe cases may require surgical or endovascular intervention.Traditional Chinese medicine,especially acupuncture for its immunomodulatory effects,holds po-tential in treatment,though definitive evidence of efficacy is needed.The management of Takayasu's arteritis faces challen-ges due to the uncertainty of disease progression and the long-term nature of treatments.Future research should focus on improving diagnostics,therapeutic approaches,and patient outcomes.This article reviews the clinical research progress on the diagnosis and treatment of Takayasu arteritis.

Takayasu arteritisEpidemiologyEtiology and pathogenesisDiagnosis and treatment progress

宋晓莉、杨欣铭、石磊

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300381 天津中医药大学第一附属医院/国家中医针灸临床医学研究中心

大动脉炎 流行病学 病因病机 诊疗进展

国家中医药管理局中医药循证能力建设项目

2019XZZX-ZJ013

2024

疑难病杂志
中国医师协会

疑难病杂志

CSTPCD
影响因子:1.171
ISSN:1671-6450
年,卷(期):2024.23(5)
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