Organ fibrosis is a common pathological marker of a variety of chronic diseases.In this paper,under the background of the study of transforming growth factor-β1(TGF-β1)mediated classical pathway,the specific molecular mech-anism of TGF-β,induced fibrosis of various organs was summarized in combination with the interaction between inflamma-tion and immune response,non-coding RNA(ncRNA)and signaling pathways.
Organ fibrosisTransforming growth factor-β1Mechanism