Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to various infec-tions,with persistently high global incidence and mortality rates.Myocardial injury induced by sepsis is among its most se-vere complications,with its complex pathophysiological mechanisms involving excessive inflammatory responses,oxidative stress,mitochondrial damage,cell apoptosis,autophagy,and coagulation dysfunction.Coagulation dysfunction plays an in-dispensable role,where its early recognition and treatment are crucial for improving cardiac function and prognosis in pa-tients.The article reviews the role of coagulation dysfunction in sepsis-induced myocardial injury(SIMI),discussing its po-tential as a new therapeutic target,providing a reference for clinical practice.
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