Chromatin remodeling is a critical mechanism for regulating gene expression and maintaining genomic stability.In recent years,with the advancement of epigenetics research,the role of chromatin remodeling in the pathogene-sis,progression,and treatment of diseases has garnered widespread attention.Particularly in diseases such as cancer,neu-rodegenerative disorders,and developmental abnormalities,the aberrant activity of chromatin remodeling factors has been demonstrated to be closely associated with disease mechanisms.