首页|老年糖尿病患者合并肌肉减少症发病机制及治疗研究进展

老年糖尿病患者合并肌肉减少症发病机制及治疗研究进展

Pathogenesis and treatment progress of sarcopenia in elderly diabetic patients

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肌肉减少症是一种与年龄相关的疾病,其特征是骨骼肌质量减少和功能丧失,被认为是2型糖尿病(T2DM)老年患者的一种新并发症.T2DM会加速肌肉质量和功能的下降,同时肌肉减少症会导致葡萄糖代谢紊乱、身体活动减少,增加糖尿病的风险.然而,T2DM与肌肉减少症之间涉及的具体机制尚未得到彻底研究.因此,文章就肌肉减少症和糖尿病相关的病理生理学机制和治疗策略作一综述,以提高老年糖尿病患者的生活质量和减少相关并发症的发生.
Sarcopenia,an age related disease characterized by loss of skeletal muscle mass and function,is consid-ered an emerging complication in older patients with type 2 diabetes mellitus(T2DM).T2DM accelerates the loss of muscle mass and function,while sarcopenia can lead to disrupted glucose metabolism,reduced physical activity,and an increased risk of diabetes.However,the specific mechanisms involved between T2DM and sarcopenia have not been thoroughly in-vestigated.Therefore,this review aims to explore the pathophysiological mechanisms and treatment strategies associated with sarcopenia and diabetes in order to improve the quality of life and reduce the occurrence of related complications in elderly people with diabetes.

Type 2 diabetes mellitusSarcopeniaDiagnosisTreatmentElderly

杨伟、王洁妤

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100053 北京,首都医科大学宣武医院老年医学科

2型糖尿病 肌肉减少症 诊断 治疗 老年人

北京市属医院科研培育计划项目首都卫生发展科研专项自主创新项目国家自然科学基金青年项目

PX20220322024-2-103381600927

2024

疑难病杂志
中国医师协会

疑难病杂志

CSTPCD
影响因子:1.171
ISSN:1671-6450
年,卷(期):2024.23(9)