Nonalcoholic fatty liver disease(NAFLD)is a common disease that causes abnormal liver function.It is usually caused by various reasons that weaken the liver's ability to metabolize fat,making it difficult to metabolize the intake of lipid substances normally,resulting in excessive deposition of fat in the liver.This has been characterized as a global public health challenge event.The prevalence of NAFLD is on the rise globally,affecting 20％ to 45％ of the general popu-lation.There is currently no approved treatment plan for the progression of the disease or the development of liver cirrhosis or hepatocellular carcinoma.With the expansion of clinical research on NAFLD,it has been found that it is closely related to Helicobacter pylori(Hp)infection.This article reviews the research progress on the mechanism of Hp infection in NAFLD,providing new methods for the clinical prevention and treatment of NAFLD.
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