Drug eluting stent(DES)are widely recommended for primary percutaneous coronary intervention(PCI).However,DES implantation can affect vascular autoregulatory function and is linked to risks of stent thrombosis and in-stent restenosis.This has led to the proposal of the"no implant intervention"concept.Drug coated balloon(DCB)release medication uniformly upon contact with the vascular endothelium,effectively inhibiting excessive intimal hyperplasia and im-proving myocardial perfusion without the need for permanent implants.While limited studies have reported on the clinical efficacy of DCB in Primary PCI(PPCI),this article provides a review of the relevant clinical research progress.
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