疑难病杂志2024,Vol.23Issue(11) :1403-1408.DOI:10.3969/j.issn.1671-6450.2024.11.024

调节性T细胞的免疫治疗研究进展

Advances in immunotherapy of regulatory T cells

樊慧明 焦沃尔 陈始明
疑难病杂志2024,Vol.23Issue(11) :1403-1408.DOI:10.3969/j.issn.1671-6450.2024.11.024

调节性T细胞的免疫治疗研究进展

Advances in immunotherapy of regulatory T cells

樊慧明 1焦沃尔 1陈始明1
扫码查看

作者信息

  • 1. 430060 武汉大学人民医院耳鼻咽喉头颈外科
  • 折叠

摘要

人体免疫系统时刻维持动态平衡,当免疫系统发生紊乱时,可导致急/慢性炎性疾病、自身免疫性疾病及移植物抗宿主病(GVHD)等多种免疫相关疾病的发生.调节性T细胞(Treg)是CD4+辅助T细胞的一类亚群,对于维持免疫稳态和预防自身免疫性疾病至关重要.文章对Treg细胞的生理作用机制、免疫治疗方法及其靶向治疗价值进行综述,旨在为后续Treg细胞的免疫治疗策略提供有益借鉴.

Abstract

The human immune system maintains dynamic balance at all times.When the immune system is disorder-ed,it can lead to acute and chronic inflammatory diseases,autoimmune diseases,graft versus host disease(GVHD)and oth-er immune-related diseases.Regulatory T cells(Treg)are a subset of CD4+helper T cells,which play an important role in maintaining immune homeostasis and preventing autoimmune diseases.In view of this,the article reviews the physiological mechanism,immunotherapy methods and the value of targeted therapy of Treg cells,aiming to provide useful reference for the subsequent immunotherapy strategies of Treg cells.

关键词

调节性T细胞/免疫治疗

Key words

Regulatory T cells/Immunotherapy

引用本文复制引用

出版年

2024
疑难病杂志
中国医师协会

疑难病杂志

CSTPCD
影响因子:1.171
ISSN:1671-6450
段落导航相关论文