Anemia is a common complication of chronic kidney disease(CKD),especially in CKD patients with ma-intenance hemodialysis.In the past,anemia was mainly thought to be related to insufficient erythropoiesis and excessive loss in patients,therefore erythropoiesis stimulators were often used for treatment.In recent years,with the deepening of re-search,new pathogenesis such as abnormal bone mineral metabolism and abnormal thyroid function have been gradually discovered,and with the development and application of new drugs such as roxadustat and enarodustat,the diagnosis and treatment situation of CKD maintenance hemodialysis-related anemia has been improved.The study reviews the characteris-tics and treatment methods of CKD maintenance hemodialysis-related anemia in order to provide new ideas for the treatment of the disease.