Mirizzi syndrome is an obstructive jaundice or cholangitis caused by external pressure on the hepatic duct caused by stones embedded in the gallbladder duct or neck of the gallbladder.Because of its lack of specific symp-toms and signs,it is easy to be confused with common biliary calculi,biliary inflammation and other diseases,increasing the occurrence of missed diagnosis or misdiagnosis.In order to improve the understanding of the disease,Mirizzi syndrome needs to be effectively examined.At present,surgery is one of the effective methods to treat Mirizzi syndrome,and laparo-scopic cholecystectomy(LC)is widely used in clinical practice.Compared with traditional open cholecystectomy,LC laparo-scopic video can carry out targeted resection of the abdomen and organs,greatly preserving the integrity of the abdominal wall muscles and abdominal tissues,and has the advantages of small incision,less pain,and faster recovery.This article re-views the research progress of Mirizzi syndrome diagnosis and LC therapy.