Since the discovery of vitamin D,there have been continuous advances in clinical research on vitamin D.In recent years,vitamin D receptors and their gene polymorphisms have become well-known in clinical practice,and research on their association with thyroid diseases has gradually increased,including toxic diffuse goiter,thyroid associated ophthal-mopathy,Hashimoto's thyroiditis,pregnancy and childbirth thyroid diseases,thyroid nodules,and thyroid cancer.This arti-cle reviews the relevant research on the association between vitamin D and its receptor gene polymorphism and thyroid dis-eases at home and abroad,in order to clarify their interactions and influencing mechanisms,and provide assistance for the feasibility of treating thyroid diseases through vitamin D supplementation.
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