Sarcopenia is a generalized,progressive age-related skeletal muscle disorder characterized by decreased muscle mass and strength,significantly impacts elderly individuals'physical activity capabilities and quality of life.Recent studies highlight that the health status of the gut microbiota is crucial for maintaining muscle mass and function.With ad-vancing age,intestinal barrier functions weaken,leading to chronic low-grade inflammation,which accelerates the depletion of muscle tissue.Probiotics,prebiotics,and synbiotics,as key components for regulating gut microbial balance,can inhibit the growth of pathogenic bacteria,reduce the production of pro-inflammatory factors,and promote the generation of short-chain fatty acids,thereby enhancing muscle anabolic processes and resisting the progression of sarcopenia.This article re-views experimental and clinical research both domestically and internationally regarding gut microbiome preparations,under-scoring their potential role in combating age-related muscle loss.
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