云南医药2024,Vol.45Issue(1) :65-68.

ALBI、NLR、CRP联合诊断肝硬化合并细菌性腹膜炎的临床价值

The clinical value of ALBI score combined with NLR and CRP in the diagnosis of liver cirrhosis complicated with spontaneous bacterial peritonitis

周嘉敏 唐源 李红纳
云南医药2024,Vol.45Issue(1) :65-68.

ALBI、NLR、CRP联合诊断肝硬化合并细菌性腹膜炎的临床价值

The clinical value of ALBI score combined with NLR and CRP in the diagnosis of liver cirrhosis complicated with spontaneous bacterial peritonitis

周嘉敏 1唐源 1李红纳1
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作者信息

  • 1. 曲靖市第一人民医院消化医学中心,云南 曲靖 655000
  • 折叠

摘要

目的 探讨ALBI评分联合NLR、CRP对肝硬化腹水患者合并SBP的诊断价值.方法 选取2018年1月-2022年9月收住曲靖市第一人民医院确诊肝硬化腹水的134例患者,分为SBP与非SBP 2组,患者的临床资料经Logistic回归分析筛选出SBP的独立危险因素,系数法建立联合模型并绘制受试者工作曲线,评估各项指标及联合模型对肝硬化合并SBP的诊断价值.结果 ALBI评分、NLR、CRP均是肝硬化患者SBP的独立危险因素.ALBI评分、NLR、CRP以及ALBI-NLR-CRP联合模型诊断 SBP 的曲线下面积分别为 0.715(95%CI:0.627~0.802,P<0.05)、0.808(95%CI:0.715~0.866,P<0.05)、0.790(95%CI:0.736~0.879,P<0.05)、0.880(95%CI:0.820~0.940,P<0.05),灵敏度分别为 66.30%、65.10%、77.10%、77.10%,特异度分别为70.60%、88.20%、72.50%、94.10%.结论 ALBI、NLR、CRP都是肝硬化腹水患者继发SBP独立的评价指标,ALBI-NLR-CRP联合模型简便、无创、价廉,用于诊断肝硬化继发SBP有重要推广应用价值.

Abstract

Objective To investigate the diagnostic value of ALBI score combined with NLR and CRP in patients with liver cirrhosis and ascites complicated with spontaneous bacterial peritonitis(SBP).Methods A total of 134 cirrhotic ascites patients admitted to the First People's Hospital of Qujing City January 2018 to September 2022 were divided into SBP group and non-SBP group.The independent risk factors of SBP were screened out by Logistic regression analysis of the patients'clinical data,and the combined model was established by coefficient method and the working curve of subjects was drawn to evaluate the diagnostic value of each index and combined model for cirrhosis complicated with SBP.Results ALBI score,NLR and CRP were independent risk factors for SBP in patients with liver cirrhosis.The area under the curve of ALBI score,NLR,CRP and ALBI-NLR-CRP combined model in the diagnosis of SBP was 0.715(95%CI:0.627-0.802,P<0.05)and 0.808(95%CI:0.627-0.802,P<0.05)respectively.0.715-0.866,P<0.05),0.790(95%CI:0.736-0.879,P<0.05),0.880(95%CI:0.820-0.940,P<0.05),the sensitivity was 66.30%,65.10%,77.10%,77.10%respectively,and the specificity was 70.60%,88.20%,72.50%,94.10%respectively.Conclusions ALBI,NRL and CRP are all independent evaluation indicators of secondary SBP in patients with liver cirrhosis and ascites.The combined model of ALBI-NLR-CRP is simple,non-invasive and inexpensive,and has important application value in the diagnosis of secondary SBP of cirrhosis.

关键词

肝硬化/自发性细菌性腹膜炎/白蛋白-胆红素评分/中性粒细胞-淋巴细胞比值/C反应蛋白

Key words

cirrhosis/spontaneous bacterial peritonitis/albumin-bilirubin score/neutrophil-lymphocyte ratio/C-reactive protein

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出版年

2024
云南医药
中华医学会云南分会

云南医药

影响因子:0.459
ISSN:1006-4141
参考文献量17
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