Prediction value of venous thrombosis leading to pulmonary embolism caused by pulmonary artery pressure and brain natriuretic peptide
Objective To measure the pulmonary artery pressure multiterm index by transthoracic echocardiography(TTE),brain natriuretic peptide and numerical value of myocardial enzymes were tested by blood,when spiral CT pulmonary angiography(CTPA)could not completed the examination of deep venous thrombosis(DVT)of lower extremities,to evaluate the predict value of the methods for acute pulmonary embolism(APE).Methods 88 hospitalized patients with APE were selected as case group and 90 healthy people with physical examination as control group.According to the values of troponin,myoglobin and BNP,the case group was divided into intermediate-risk and low-risk groups;The control group was the group without pulmonary embolism.Based on CTPA,the levels of TTE,BNP and myocardial enzyme in the three groups were compared,and the operating characteristic curve was drawn.Results There were statistically significant differences in pulmonary artery pressure and BNP between the middle-risk group and the control group(P＜0.05),pulmonary artery pressure(OR=0.751,95％CI=0.646～0.881,P＜0.001)and BNP(OR=0.957,95％CI=0.931～0.985,P=0.003).The ROC curve showed that pulmonary artery pressure AUC=0.900(95％CI=0.842～0.958)and BNP AUC=0.896(95％CI=0.826～0.966).According to Jordon index,the optimal cut-off value of pulmonary artery pressure was 33mmHg and BNP=47.52pg/mL.Conclusions Pulmonary artery pressure and brain natriuretic peptide are most likely independent predictors of deep vein thrombosis of lower extremity complicated with acute pulmonary embolism,and can be considered as important references for predicting acute pulmonary embolism.
deep vein thrombosis of lower extremityacute pulmonary embolismtransthoracic echocardiographybrain natriuretic peptidemyocardial enzymes
NETL
NSTL
万方数据
维普
