Analysis on the correlation analysis between CD40 gene polymorphism and hypertensive heart disease
Objective The aim of this study was to investigate whether polymorphisms in two SNPS of CD40,rs4810485 and rs1883832,are associated with genetic susceptibility to HHD.Methods rs4810485 and rs1883832 SNPS of CD40 gene were genotyped by PCR-RFLP.Results The GG genotype of CD40 gene rs4810485 and the G allele were significantly increased in hypertensive heart disease,and the G allele was a susceptibility gene for hypertensive heart disease.Conclusions The GG genotype is significantly increased in HHD,and the G allele is the susceptibility gene for HHD.
NETL
NSTL
万方数据
维普
