Study on the application of IVIM-DWI for different anatomical parts of normal pancreas and acute pancreatitis
Objective Study the difference by the application of voxel incoherent motion diffusion-weighted imaging for normal pancreas and acute pancreatitis,and explore the difference and significance of parameters in different anatomical parts of normal pancreas and acute pancreatitis.Methods 29 healthy volunteers and 33 acute pancreatitis patients underwent upper abdominal MRI and IVIM-DWI scanning to measure ADC,f,D and D*values of the head,neck and tail of the pancreas.Single factor variance,LSD test and independent sample t-test were used to compare and analyze the difference between normal pancreas and AP pancreas parameters.Results There were significant differences in ADC and f-values among different anatomical parts of normal pancreas,but no statistically significant difference in the parameters of different anatomical parts of diffuse AP patients.The ADC,f and D values in AP patients were lower than those in normal pancreas,and D*values were higher than those in normal pancreas,and the differences were statistically significant(P＜0.05).The ADC and f-values of patients with limited AP were ranked from high to low as follow:NP group＞non-lesion part＞lesion part,with statistically significant differences.Conclusions The ADC,f,D and D*values in different anatomical parts of pancreas may be used as indicators for identification of acute pancreatitis,in which f value is the main parameter for indirect evaluation of microcirculation perfusion in different anatomical parts of pancreas.
NETL
NSTL
万方数据
