Efficacy and renal safety of entecavir in the treatment of chronic hepatitis B complicated with type 2 diabetes
Objective To investigate the efficacy and renal safety of entecavir in the treatment of chronic hepatitis B(CHB)complicated with type 2 diabetes mellitus(T2DM).Methods A total of 72 patients with CHB complicated with T2DM admitted to our hospital from February 2021 to February 2023 were divided into two groups.The control group was treated with tenofovir fumarate,and the study group was treated with entecavir.Clinical efficacy,renal function,glucose and lipid metabolism and liver function of the two groups were observed and analyzed.Results Compared with the control group,the clinical effect of the study group was better,SCr and BUN levels were lower,eGFR levels were higher,FBG and HbA1c levels were lower,ALT,AST and TBIL levels were lower,and the differences were statistically significant(P＜0.05).Conclusions Patients treated with entecavir can achieve a relatively ideal antiviral treatment effect,and has a high safety on the kidney,which is worthy of application.
万方数据
维普
