Objective To study the chemical constituents of the ethyl acetate extraction of Aralia chinensis Linn.var.nuda Nakai.Methods The ethyl acetate part of 70％ethanol extract of A.chinensis Linn.var.nuda Nakai was purified by silica gel,ODS,Sephadex LH-20,and semi-preparative HPLC,and the structures of the compounds were identified by the physicochemical properties and spectral data.Results Twelve compounds were isolated and identified as phthalic acid,bis-(2,5-dimethylhexyl)ester(1),(9E)-8,11,12-trihydroxyoctadecenoic acid methyl ester(2),methyl(9S,10R,11E,13R)-9,10,13-trihydroxyoctadec-11-enoate(3),capillasterolide(4),hexacosane(5),(-)-loliolide(6),methyl hematinate(7),tyraminel(8),(S)-methyl 2-acetamido-3-phenylpropanoate(9),3-hydroxy-4-methoxybenzoic acid(10),vanillic acid(11),and p-hydroxybenzoic acid(12).Conclusion Compounds 1-10 were isolated from this genus Aralia for the first time,and compounds 1-11 were first isolated from the plant.
Aralia chinensis var.nuda Nakaichemical constituentsisolation and identification
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