摘要
四数九里香作为传统民族药,含有挥发油、黄酮、生物碱和香豆素等成分,表现出抗炎、镇痛、趋避杀虫和抗肿瘤等多重药理作用.本文对四数九里香化学成分、药理作用以及潜在毒性进行简要综述,并提出其药效物质基础、作用机制以及慢性毒性等方面仍值得深入研究.对四数九里香功能特性开展系统深入的挖掘并将其应用到创新药物的开发中,对于进一步提高四数九里香产品附加值、拓展其应用领域具有重要意义.
Abstract
As a traditional ethnic medicine,Murraya tetramera Huang contains components such as volatile oils,flavonoids,alkaloids,and coumarins,which exhibit multiple pharmacological effects,including anti-inflammatory,analgesic,insecticidal,and antitumor activities.This article provides a brief overview of the chemical constituents,pharmacological effects,and potential toxicity of M.tetramera Huang.It suggests that further in-depth research is warranted to explore its pharmacological substance foundation,mechanism of action,and chronic toxicity.The systematic exploration of the functional characteristics of M.tetramera Huang and their application in the development of innovative drugs is of significant importance in enhancing the added value of M.tetramera Huang products and expanding their application fields.
基金项目
云南省重大科技专项(202302AA310014)
澜湄区域资源创新药物研究与开发云南省教育厅工程研究中心(2022YGG03)
昆明市国际(对外)科技合作基地项目(GHJD-2021030)