首页|中药皂苷类成分治疗神经系统疾病的研究进展

中药皂苷类成分治疗神经系统疾病的研究进展

Research Progress of TCM Saponins in the Treatment of Nervous System Diseases

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神经系统疾病的发病率逐年增加,以头痛、记忆力减退、瘫痪和癫痫发作为典型症状,已成为全世界第二大死亡原因.由于病因复杂,目前临床上对于各类神经系统疾病的治疗方法仍以保守治疗为主.寻找和开发新型的神经系统疾病治疗药物成为热点问题.皂苷是一类常见的中药活性成分,多种皂苷类成分已明确具有良好的神经保护作用,如人参皂苷、黄芪皂苷、柴胡皂苷、薯蓣皂苷等.通过对近年来有关中药皂苷类成分的神经保护作用研究的文献进行查阅、分析和总结,以期为神经系统疾病治疗药物的研究与开发提供参考.
The incidence of nervous system diseases in the increase by years,with headache,memory loss,pa-ralysis and epilepsy as the typical symptoms,has become the second leading cause of death in the world.Due to the complex pathogenesis,the current clinical treatment of various neurological diseases is still conservative.Finding and developing new therapeutic drugs for nervous system diseases has become a hot issue.Saponins are a kind of common active ingredients in traditional Chinese medicine.A variety of saponins have been shown to have good neuroprotective effects,such as ginsenoside,astragalus saponin,saikosaponin,diosgenin,etc.This paper reviewes,analyzes and summarizes the studies on the neuroprotective effects of Chinese saponins in recent years in order to provide reference for the research and development of drugs for the treatment of nervous system diseases.

Chinese Materia MedicalSaponinsNeuroprotective Effect

刘紫薇、李琪、刘丽芳

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中国药科大学,江苏南京 210009

中药 皂苷 神经保护

国家自然科学基金江苏省研究生科研创新计划

82074089KYCX21_0686

2022

云南中医中药杂志
云南省中医中药研究院,云南省中医药学会

云南中医中药杂志

影响因子:0.598
ISSN:1007-2349
年,卷(期):2022.43(11)
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