Meta-analysis of the Effectiveness of Yinqiao Powder in the Treatment of Acute Upper Respiratory Tract Infection
Objective:To systematically evaluate the effectiveness of Yinqiao Powder in the treatment of acute up-per respiratory tract infection and to provide evidence for its clinical application.Methods:The randomized controlled trials of Yinqiao Powder in the treatment of acute upper respiratory tract infection were searched on CNKI,WanFangDa-ta,VIP,CBM,Pubmed,Web of Science,The Cochrane Library and Clinical Trials.gov databases by computer and the quality screening and data extraction were performed for the included studies,and the meta-analysis was performed by using RevMan5.3 software.Results:A total of 17 valid studies were included.The results of the meta-analysis showed that the total clinical response rate of Yinqiao Powder experimental group was better than that of control group[RR=1.19,95％CI(1.15,1.22),P＜0.00001].The duration of fever reduction was shorter than that of control group[SMD=-0.36,95％CI(-0.71,-0.01),P=0.04].The duration of treatment was shorter than that of con-trol group[SMD=-2.02,95％CI(-3.24,-0.80),P=0.001].The time for body temperature to return to normal was shorter than that of control group[SMD=-2.67,95％CI(-4.06,-1.28),P=0.0002].The recovery rate was better than that of control group[RR=1.54,95％CI(1.35,1.75),P＜0.00001].The recurrence rate was lower than that of control group[RR=0.06,95％CI(0.01,0.30),P=0.0008].The disappearance time of throat pain was shorter than that of control group[SMD=-3.93,95％CI(-7.70,-0.17),P=0.04].The difference between the two groups was statistically significant.Conclusion:Based on current clinical evidence,Yinqiao Powder has a good effect and safety in the treatment of acute upper respiratory tract infection.However,due to the small number of includ-ed samples and low quality,the authenticity and reliability of this conclusion may be affected and more large samples and high-quality randomized controlled trials are needed to confirm it.
万方数据
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