首页|基于中医传承计算平台分析中医药治疗糖尿病周围神经病变的用药规律

基于中医传承计算平台分析中医药治疗糖尿病周围神经病变的用药规律

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目的 挖掘中医药治疗糖尿病周围神经病变的用药规律,以期为临床治疗该病提供思路.方法 以中国知网、万方、维普期刊数据库收录的2018年-2022年文献为资料来源,收集其中所涉及的相关方剂,建立相应的数据库,将方剂中涉及到的药物逐条录入"中医传承计算平台管理系统",对药物的频率、药性、药味进行统计分析,运用该平台软件的关联规则、聚类分析等统计方法进行数据的统计分析,挖掘相关用药规律.结果 共筛选出符合条件的方剂151首,共涉及到184味中药,其药性以温、平、寒为主,药味以甘、苦、辛为主,按照使用频次排序,由多到少依次为:补虚药、活血化瘀类、解表类等;所涉及的高频中药(频次>40次)共计12味.其中黄芪占首位,其次是当归、鸡血藤、桂枝、川芎、甘草、地龙、牛膝、红花、赤芍、甘草、生地等.进一步对高频药物进行关联分析,挖掘出高频药物关联规则8条,并将高频药物聚为3类.结论 中医药治疗糖尿病周围神经病变注重补虚泻实,标本兼治,多以补气、健脾益肾为主,兼顾活血化瘀、通络止痛.
Analysis of the Medication Rules in the Treatment of Diabetic Peripheral Neuropathy with Traditional Chinese Medicine Based on TCM Inheritance Computing Platform
Objective:To explore the medication rules of traditional Chinese medicine in the treatment of diabetic peripheral neuropathy and to provide ideas for clinical treatment of the disease.Methods:The literature from 2018 to 2022 collected from CNKI,Wanfang and Weipu periodical databases were used as data sources and the related pre-scriptions were collected and a corresponding database was established.The herbs involved in the prescriptions were recorded into the"TCM inheritance Computing Platform Management System"one by one to conduct statistical analysis on their frequency,property and taste.Statistical methods such as association rules and cluster analysis of the platform software were used for statistical analysis of the data,and the related medication rules were found.Results:A total of 151 prescriptions meeting the conditions were selected,involving a total of 184 herbs.The properties were mainly warm,moderate and cold,and the tastes were mainly sweet,bitter and pungent.According to the frequency of usage,the order from most to least followed as,tonifying deficiency medicine,promoting blood circulation to remove stasis and relieving exterior syndrome.The involved high-frequency herbs(frequency>40 times)totaled 12 flavors.As-tragalus was the first,followed by Angelica,Spatholobi,Cassia twig,Ligusticum,Licorice,Lumbricus,Achyranthes,Safflower,Paeoniae,Rehmannia and so on.The association analysis of high-frequency herbs was further carried out,and 8 high-frequency herb association rules were found,and the high-frequency herbs were grouped into 3 catego-ries.Conclusion:The treatment of diabetic peripheral neuropathy with traditional Chinese medicine should focus on tonifying deficiency and purging excess,treating both symptoms and root causes,mainly tonifying qi,invigorating spleen and nourishing kidney as well as taking into account promoting blood circulation to remove blood stasis and acti-vating meridians to stop pain.

Diabetic Peripheral NeuropathyData MiningCluster AnalysisMedication Rule

张琳婷、颜青、惠旭昊、王凯丽、杨青、党毓起

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宁夏医科大学,宁夏银川 750000

宁夏医科大学附属银川市中医医院,宁夏银川 750000

糖尿病周围神经病变 数据挖掘 聚类分析 用药规律

银川市科技计划项目

2021-SF-002

2024

云南中医中药杂志
云南省中医中药研究院,云南省中医药学会

云南中医中药杂志

影响因子:0.598
ISSN:1007-2349
年,卷(期):2024.45(2)
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