Study on the Medication Rules of Chinese Herbal Compound for External Treatment of Eczema Based on National Patent Database
Objective:To analyze the patent medication rules of Chinese herbal compound for external treatment of eczema and to provide reference for the research and development of new Chinese medicine.Methods:The Chinese herbal compound patents on the external treatment of eczema in the patent database of the State Intellectual Property Office until April 10,2022 were searched and input into Excel 2019 for selection.SPSS Modeler 18.0 software and SPSS Statistics 25.0 software were used for visual analysis,association rule analysis,cluster analysis and association rule network diagram display.Results:A total of 142 Chinese herbal compound patents were included through screen-ing,involving 445 herbal flavors.Single Sophorae 71 times(50.00％),Phelloderma 53 times(37.32％)and Fruc-tus cnidii 51 times(35.92％)were the top three herbs with the highest frequency.The main effects of Chinese herbal compound were heat-clearing medicine,wind-dampness medicine and blood-activating medicine.The properties were mainly moderate,cold and warm,and the tastes were mainly bitter,pungent and sweet,which mainly belong to the liver,lung and stomach channels.The association rules with high confidence was"Sophorae-Kochiae,Dictamni,Sophorae-Phellodendri,Dictamn,Sophorae-Stemonae"and so on.The cluster analysis obtained 7 categories,such as"Atractylodes,Peony bark,Kochiae""Sikeris,Angelica,Lithosermi"and so on.Conclusion:Chinese herbal compound patent for external treatment of eczema has rules to follow.The basic principles of clearing heat and remo-ving dampness,dispelling wind and relieving itch are in line with the theoretical basis of TCM treatment of eczema.
万方数据
维普
