针刺治疗脑卒中后中枢性疼痛的系统评价和Meta分析
A Systematic Review and Meta-Analysis of Acupuncture in the Treatment of Central Pain after Stroke
王志红 1王嘉麟2
作者信息
- 1. 北京中医药大学,北京 100029
- 2. 北京中医药大学东方医院,北京 100078
- 折叠
摘要
目的 系统评价针刺治疗脑卒中后中枢性疼痛的疗效.方法 检索中国知网、万方、维普及PubMed等数据库中所有针刺治疗脑卒中后中枢性疼痛的临床随机对照试验,检索时间为建库起至2022年12月.经严格筛选,提取数据并评价纳入研究的偏倚风险后,运用Rev Man5.4软件进行Meta分析.结果 最终纳入文献12篇,病例1076例.8篇选用总有效率进行评价,结果显示:OR=3.17,95％CI(2.16,4.64),Z=5.92(P＜0.0001).10篇以疼痛视觉模拟评分(VAS)作为结局指标,结果显示:MD=-1.18,95％CI(-1.53,-0.83),Z=6.58(P＜0.00001).4篇采用匹兹堡睡眠质量指数(PSQI)作为结局指标,结果显示:MD=-2.63,95％CI(-3.16,-2.10),Z=9.73(P＜0.00001).2 篇采用改良 Bankin 量表(MRS)作为结局指标,结果显示:MD=-0.60,95％CI(-0.78,-0.41),Z=6.93(P＜0.00001).结论 针刺治疗脑卒中后中枢性疼痛可以有效缓解疼痛,改善患者睡眠质量,促进损伤神经功能的恢复.
Abstract
Objective:To systematically evaluate the effect of acupuncture in the treatment of central pain after stroke.Methods:All randomized controlled clinical trials of acupuncture in the treatment of central pain after stroke were searched from CNKI,Wanfang,VIP and PubMed databases from the database establishment to December 2022.After rig-orous screening and data extraction were made and the risk of bias in included studies were evaluated,a meta-analysis was performed by using Rev Man5.4 software.Results:12 literature with 1076 cases were included.The total effective rate of 8 articles was evaluated,and the results showed that OR=3.17,95％CI(2.16,4.64),Z=5.92(P＜0.0001).The visual analogue score(VAS)in 10 articles was used as the outcome index,and the results showed that MD=-1.18,95％CI(-1.53,-0.83),Z=6.58(P＜0.00001).In 4 articles,Pittsburgh Sleep Quality Index(PSQI)was used as the outcome index,and the results showed that MD=-2.63,95％CI(-3.16,-2.10),Z=9.73(P＜0.00001).In two ar-ticles,the modified Bankin Scale(MRS)was used as the outcome index,and the results showed that MD=-0.60,95％CI(-0.78,-0.41),Z=6.93(P＜0.00001).Conclusion:Acupuncture treatment of central pain after stroke can effec-tively relieve pain,improve sleep quality and promote the recovery of injured nerve function.
关键词
针刺/脑卒中后中枢性疼痛/Meta分析/系统评价Key words
Acupuncture/Central Pain after Stroke/Meta-Analysis/Systematic Evaluation引用本文复制引用
基金项目
首都临床诊疗技术研究及示范应用项目(Z191100006619074)
基本科研业务费重点攻关项目(2020)(2020-JYB-ZDGG-130)
出版年
2024
NETL
NSTL
万方数据