首页|基于"肺朝百脉"探讨肾素—血管紧张素系统在肺间质纤维化中的意义

基于"肺朝百脉"探讨肾素—血管紧张素系统在肺间质纤维化中的意义

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"肺朝百脉"是指以肺气宣发肃降为动力,以肺生血为物质基础,调节周身血脉.肾素血管紧张素系对血管的作用同"肺朝百脉"有着密切联系.肾素血管紧张素系统通过ACE-Ang Ⅱ-AT1R轴与ACE2-Ang-(1-7)-MasR轴在肺间质纤维化过程中起重要调节作用.基于"肺朝百脉"理论,阐述肾素血管紧张素系统在肺间质纤维化形成中的意义,为中医药改善间质性肺疾病提供新的思路和研究方法.
Exploration of the Significance of Renin-angiotensin System in Pulmonary Interstitial Fibrosis Based on the"Convergence of Vessels in the Lung"
"The Convergence of Vessels in the Lung"refers to the pulmonal-qi dispersion and descending as the driving force and the pulmonal-blood production as the material basis to regulate blood vessels throughout the body.The effect of renin-angiotensin system on the blood vessels is closely related to the"the Convergence of Vessels in the Lung".The renin-angiotensin system plays an important regulation role in the process of pulmonary interstitial fibrosis through ACE-Ang Ⅱ-AT1 R axis and ACE2-Ang-(1-7)-MASr axis.Based on the theory of"the Con-vergence of Vessels in the Lung",the significance of the renin-angiotensin system in the formation of interstitial pul-monary fibrosis is expounded,providing a new idea and research method for improving interstitial pulmonary diseases with traditional Chinese medicine.

Interstitial Lung DiseasePulmonary Interstitial Fibrosis"Convergence of Vessels in the Lung"Dispersion and DescendingPulmonal-blood ProductionRenin-angiotensin SystemAngiotensin Ⅱ

满孝君、马君

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山东中医药大学,山东济南 250014

山东中医药大学附属医院,山东济南 250014

间质性肺疾病 肺间质纤维化 肺朝百脉 宣发肃降 肺生血 肾素血管紧张素系统 血管紧张素Ⅱ

山东省中医药科技发展计划项目

2019-0127

2024

云南中医中药杂志
云南省中医中药研究院,云南省中医药学会

云南中医中药杂志

影响因子：0.598
ISSN：1007-2349
年,卷(期)：2024.45(9)
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