基于"肺朝百脉"探讨肾素—血管紧张素系统在肺间质纤维化中的意义
Exploration of the Significance of Renin-angiotensin System in Pulmonary Interstitial Fibrosis Based on the"Convergence of Vessels in the Lung"
满孝君 1马君2
作者信息
- 1. 山东中医药大学,山东济南 250014
- 2. 山东中医药大学附属医院,山东济南 250014
- 折叠
摘要
"肺朝百脉"是指以肺气宣发肃降为动力,以肺生血为物质基础,调节周身血脉.肾素血管紧张素系对血管的作用同"肺朝百脉"有着密切联系.肾素血管紧张素系统通过ACE-Ang Ⅱ-AT1R轴与ACE2-Ang-(1-7)-MasR轴在肺间质纤维化过程中起重要调节作用.基于"肺朝百脉"理论,阐述肾素血管紧张素系统在肺间质纤维化形成中的意义,为中医药改善间质性肺疾病提供新的思路和研究方法.
Abstract
"The Convergence of Vessels in the Lung"refers to the pulmonal-qi dispersion and descending as the driving force and the pulmonal-blood production as the material basis to regulate blood vessels throughout the body.The effect of renin-angiotensin system on the blood vessels is closely related to the"the Convergence of Vessels in the Lung".The renin-angiotensin system plays an important regulation role in the process of pulmonary interstitial fibrosis through ACE-Ang Ⅱ-AT1 R axis and ACE2-Ang-(1-7)-MASr axis.Based on the theory of"the Con-vergence of Vessels in the Lung",the significance of the renin-angiotensin system in the formation of interstitial pul-monary fibrosis is expounded,providing a new idea and research method for improving interstitial pulmonary diseases with traditional Chinese medicine.
关键词
间质性肺疾病/肺间质纤维化/肺朝百脉/宣发肃降/肺生血/肾素血管紧张素系统/血管紧张素ⅡKey words
Interstitial Lung Disease/Pulmonary Interstitial Fibrosis/"Convergence of Vessels in the Lung"/Dispersion and Descending/Pulmonal-blood Production/Renin-angiotensin System/Angiotensin Ⅱ引用本文复制引用
基金项目
山东省中医药科技发展计划项目(2019-0127)
出版年
2024
NETL
NSTL
万方数据