摘要
目的 通过Meta分析研究近视与中医体质的相关性,初步明确近视患者中医体质分布规律,为从体质角度防治近视提供依据.方法 通过检索国内外文献数据库,纳入符合要求的近视与中医体质相关性文献,应用Stata17软件进行Meta分析,结果以分布率、比值比及其95％置信区间表达效应值.结果 共纳入22项研究,近视人群占比较大的有阳虚质13％、气虚质12％、阴虚质11％、气郁质10％,中低度近视气虚质占比13％,阳虚质占比12％,高度及病理性近视阳虚质占比20％、阴虚质占比15％,组间比较气虚质、气郁质、阳虚质、阴虚质为近视人群的危险因素,平和质是近视人群的保护因素,其余体质差异无统计学意义.结论 气虚质、气郁质、阳虚质、阴虚质是近视人群主要体质类型,其与正常人群存在明显差异,这可能成为调整体质防控近视的切入点.
Abstract
Objective:To study the correlation between myopia and TCM constitution types through a Meta-a-nalysis,identifying the distribution patterns of TCM constitutions among myopic patients and to provide a basis for the prevention and treatment of myopia from the perspective of constitution.Methods:Relevant literature on myopia and TCM constitution correlation was retrieved from domestic and international databases and the studies meeting the inclu-sion criteria were analyzed using Stata 17 software,and effect sizes were expressed as distribution rates,odds ratios,and 95％confidence intervals.Results:A total of 22 studies were included.Among myopic individuals,the most prevalent constitution types were Yang-deficiency(13％),Qi-deficiency(12％),Yin-deficiency(11％),and Qi-stagnation(10％).For mild to moderate myopia,Qi-deficiency accounted for 13％,and Yang-deficiency for 12％.For severe and pathological myopia,Yang-deficiency constituted 20％,and Yin-deficiency 15％.Compari-sons between groups indicated that Qi-deficiency,Qi-stagnation,Yang-deficiency,and Yin-deficiency were risk factors for myopia,while a balanced constitution was a protective factor.No statistically significant differences were ob-served for other constitution types.Conclusion:Qi-deficiency,Qi-stagnation,Yang-deficiency,and Yin-defi-ciency are the primary constitution types among myopic individuals,differing significantly from those in the general population.These findings may provide a starting point for the prevention and control of myopia through constitution adjustment.
维普
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