Study on the Effect of Pulmicort Respules Combined with Aerobic Exercise on the Rehabilitation of Bronchial Asthma
Objective Observing the effect of combination of pulmicort respules and aerobic exercise on improving the rehabilitation effect of patients with bronchial asthma.Methods This article was a prospective study,selecting 100 patients with bronchial asthma admitted to Zhengzhou 460 Hospital from October 2020 to March 2023 as the research subjects.They were randomLy divided into a conventional group and a combination group using a computer random number table method,with 50 cases in each group.The conventional group was treated with conventional medication combined with aerobic exercise,while the combination group was treated with adjuvant therapy of pulmicort respules on based of conventional group.The symptom relief time,inflammation response,improvement of lung function before and after treatment,improvement of asthma control test(ACT)score,and treatment safety were compared between the two groups.Results The cough disappearance time,dyspnea relief time,lung rale disappearance time,wheezing disappearance time,and hospitalization time of the combination group were(6.44±2.12)d,(1.82±0.46)d,(3.36±0.77)d,(2.51±0.46)d,and(14.49±3.46)d,lower than the conventional group[(9.77±3.42)d,(2.35±0.26)d,(4.49±1.26)d,(3.23±0.46)d,and(17.72±5.36)d];under different treatment regimens,the expression levels of Toll like receptor 2(TLR2)and TLR4 in the combination group after treatment were(1.35±0.41)and(0.85±0.21),lower than the conventional group[(1.77±0.45)and(1.18±0.36)];the first second forced expiratory volume percentage(FEV1),forced vital capacity(FVC),and maximum ventilation volume per minute(MVV)of the combination group after 30 days of treatment were(58.65±10.27)%,(2.75±0.36)L,and(68.82±10.31)L/min,higher than the conventional group[(52.11±10.44)%,(2.21±0.25)L,and(62.44±10.63)L/min];the ACT scores of the combined group after 7 days,14 days,and 30 days of treatment were(17.23±4.49)points,(21.77±5.42)points,and(26.33±5.49)points,higher than the conventional group[(14.33±3.45)points,(18.28±5.16)points,and(23.19±5.25)points];the incidence of adverse reactions in the combination group was 8.00%(4/50),lower than 24.00%(12/50)(P<0.05).Conclusion Pulmicort respules combined with aerobic exercise can accelerate the rehabilitation process of patients with bronchial asthma,improve airway inflammation and lung function,control asthma symptoms,enhance rehabilitation effectiveness,and enhance treatment safety,all of which have positive significance.
Bronchial asthmaPulmicort respulesAirway inflammationLung functionAsthma control test
万方数据
维普
