Analysis of 120 Adverse Drug Reaction Reports of Antibiotics in Obstetrics and Gynecology of Our Hospital from 2021 to 2022
Objective To explore the analysis of 120 adverse drug reactions(ADRs)reports of antibiotics in the obstetrics and gynecology department of Duchang Maternity and Child Health Care Hospital from 2021 to 2022,and provide reference for the rational use of antibiotics in clinical practice.Methods Retrospective selection of 600 patients treated with antibiotics in the obstetrics and gynecology department of the hospital from January 2021 to December 2022.Among them,120 patients had adverse reactions to antibiotics,with a drug adverse reaction rate of 20%.The occurrence time,administration route,type of antibiotics,and affected organs of ADR were analyzed;record the clinical manifestations and outcomes of patients with adverse reactions to antibiotics,and develop corresponding measures for intervention.Results All enrolled patients were treated with antibiotics,with an average of(5.72±0.91)days of medication;among the patients,97 cases(80.83%)of ADR occurred within 1 day of medication;the main route of administration is intravenous drip(93.33%);120 gynecological and obstetric patients used more types of antibiotics,with cephalosporins and nitroimidazoles being the top two,accounting for 66 cases(55.00%)and 24 cases(20.00%),respectively.ADR patients have relatively more organ involvement,and the top three were gastrointestinal reactions,neurological and skin reactions,accounting for 33 cases(27.50%),28 cases(23.33%),and 24 cases(20.00%),respectively;117 cases of ADR improved or were cured after treatment,and 3 patients were transferred to a higher-level hospital for diagnosis and treatment.Conclusion ADR was mainly distributed in patients who received intravenous drip medication,most patients recovered after discontinuing medication.Hospitals should strengthen key drugs and obstetrics and gynecology pharmacy monitoring to reduce the incidence of adverse reactions.
Obstetrics and gynecologyAntibacterial drugsAdverse drug reactionReport analysisReasonable drug use
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