Effects of Compound Pearl Acne Tablets on Skin Lesion Conditions and GAGS Scores in Patients with Common Acne Vulgaris
Objective To explore the effects of compound pearl acne tablets on skin lesions and GAGS scores of patients with acne vulgaris(AV).Methods Ninety-six AV patients who at Jingdezhen Dermatology Hospital from June 2022 to June 2023 were selected and divided into the experimental group and the conventional group,each with 48 cases by random number method.The conventional group was treated with doxycycline capsules,and on its basis,the experimental group was treated with compound pearl acne tablets,all treated for 8 weeks,compare the skin lesions,GAGS scores and inflammatory cytokine levels of the two groups.Results The color of skin lesions,nature of skin lesions,swelling and pain scores of skin lesions were reduced in both groups after treatment,and the experimental group were lower than those in the conventional group(P<0.05);GAGS scores of skin lesions,nature of skin lesions,swelling and pain scores of skin lesions in the experimental group were reduced in both groups after treatment,and the experimental group were lower than those in the conventional group(P<0.05);the levels of interleukin(IL)-17,tumor necrosis factor-α(TNF-α),and IL-1α were all reduced,were lower in the experimental group compared with those in the conventional group(P<0.05).Conclusion Compound pearl acne tablets for AV can antagonize the expression of inflammatory cytokines,reduce the GAGS score,and promote the improvement of skin lesion symptoms.
Acne vulgarisCompound pearl acne tabletsSkin lesionsGAGS score
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