Effects of Yiqi Weixue Tablets Combined with Shengxuebao Mixture on Red Blood Cell Parameters of Pregnant Women with α-thalassemia and Physical Growth of Newborns
Objective To explore the effect of yiqi weixue tablets combined with shengxuebao mixture on red blood cell parameters during pregnancy and physical growth of newborns in pregnant women with α-thalassemia.Methods The clinical data of 70 pregnant patients with α-thalassemia who were admitted to Xinfeng County People's Hospital from January 2020 to January 2023 were retrospectively analyzed,and they were divided into the control group(n=35)and the observation group(n=35)according to medication regimen.The control group was treated with shengxuebao mixture,while the observation group was treated with yiqi weixue tablets combined with shengxuebao mixture,both groups were treated for 8 consecutive weeks.The therapeutic effect,erythrocyte parameters,hematopoietic cytokines,neonatal physical growth and drug safety were compared between the two groups.Results The treatment effective rate of the observation group was 91.43%,which was higher than that of the control group 71.43%(P<0.05).After 8 weeks,MCH,MCV,RBC,Hb and FER in the two groups were all higher than those before treatment(P<0.05),and the above indexes in the observation group were higher than those in the control group(P<0.05);the levels GM-CSF and SCF in the observation group were higher than those in the control group(P<0.05).The length,head circumference and birth weight of neonates in the observation group were higher than those in the control group(P<0.05).The incidence of adverse reactions in the two groups was 17.17%and 11.43%,there was no statistical difference(P>0.05).Conclusion Yiqi weixue tablets combined with shengxuebao mixture can effectively improve the red blood cell parameters of pregnant women with α-thalassaemia during pregnancy,enhance their hematopoietic cell function,and promote the physical growth of newborns,which is effective and safe.
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