Effects of Modified Sangbaipi Decoction Combined with Shashen Maidong Decoction on Lung Function and Exercise Tolerance in Patients with Lung Distention(Phlegm-heat Stagnation Lung Syndrome)
Objective To investigate the effects of modified sangbaipi decoction combined with shashen maidong decoction on lung function and exercise tolerance in patients with lung distention(phlegm-heat stagnation lung syndrome).Methods A total of 86 patients with lung distention(phlegm-heat stagnation lung syndrome)admitted to Leping Hospital of Traditional Chinese Medicine from October 2021 to August 2023 were divided into control group(43 cases)and treatment group(43 cases)by drawing lots.The control group was given conventional treatment,and the treatment group was given modifide sangbaipi decoction combined with shashen maidong decoction on the basis of control group.The therapeutic effect,lung function index,exercise tolerance and inflammation index were compared between the two groups.Results The total effective rate of treatment group was higher than that of control group,the difference was statistically significant(P<0.05).After 2 courses of treatment,forced vital capacity(FVC),maximum expiratory flow(MEF),forced expiratory volume in the first second(FEV1)and 6 min walking test(6MWT)in the treatment group were higher than those in the control group.The levels of transforming growth factor-β1(TGF-β1),interleukin-6(IL-6)and C-reactive protein(CRP)were lower than those of control group,and the difference were statistically significant(P<0.05).Conclusion Modified sangbaipi decoction combined with shashen maidong decoction has good therapeutic effect on patients with lung distension(phlegm-heat stagnation lung syndrome),which can improve lung function,increase exercise tolerance and reduce inflammation.
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