Effect of Nalbuphine Hydrochloride Combined with Propofol on Pain Degree and Hemodynamic Indexes in Patients Undergoing Painless Gastroenteroscopy
Objective To analyze the effect of nalbuphine hydrochloride combined with propofol anesthesia on patients undergoing painless gastroenteroscopy.Methods 96 patients with painless gastroenteroscopy admitted to Yingtan People's Hospital from September 2021 to September 2023 were selected and divided into two groups according to random number table method,48 cases in each group.The control group was anesthetized with propofol,while the observation group was anesthetized with a combination of nalbuphine hydrochloride and propofol.Anesthesia related indexes,pain degree,hemodynamics and adverse reactions were compared between the two groups.Results In the observation group,the recovery time of spontaneous respiration,the opening time of eyes,and the recovery time of orientation were shorter than the control group,and the dosage of propofol was less than that of the control group.The incidence of adverse reactions was 6.25%lower than the control group 20.83%.After being awake for 5 min and 30 min,the VAS scores of the observation group were lower than those of the control group(P<0.05).Before anesthesia,the heart rate(HR)and mean arterial pressure(MAP)of the two groups were similar(P>0.05),HR and MAP in observation group were higher than those in control group at 5 min after anesthesia and after surgery(P<0.05).Conclusion Nalbuphine hydrochloride combined with propofol can relieve pain,stabilize hemodynamics,promote recovery and reduce adverse reactions in patients with painless gastroenteroscopy.
NETL
NSTL
万方数据
