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临床药师对儿科抗菌药物使用强度及使用率的干预效果

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目的 为分析临床药师干预对儿科抗菌药物使用强度及使用率的影响。方法 本研究采用非同期对照试验,收集黔西南州人民医院儿科2021年1月至12月(干预前)、2022年1月至12月(干预后)儿科住院患儿抗菌药物使用率、使用强度,进行比较。结果 干预后抗菌药物使用率(51。66±2。95)%,低于干预前(57。01±2。64)%,差异有统计学意义(P<0。05)。干预后抗菌药物使用强度(15。63±1。87)规定日剂量(DDDs),低于干预前(18。25±1。73)DDDs,差异有统计学意义(P<0。05)。临床药师干预后儿科抗菌药物处方不合理处方发生率3。83%,低于干预前2。00%(P<0。05)。干预后抗菌药物不良反应发生率0。47%,低于干预前0。84%(P<0。05)。干预后患儿家属对药学工作满意度96。39%,高于干预前89。17%(P<0。05)。结论 临床药师干预能够提高儿科抗菌药物合理使用水平,降低药物使用强度及使用率,并可减少药品不良反应发生,更好保证患儿用药安全。
The Intervention Effect of Clinical Pharmacist on the Intensity and Utilization Rate of Pediatric Antibiotics
Objective To explore the effect of clinical pharmacists'intervention on the intensity and utilization rate of pediatric antibiotics.Methods This study collected the utilization rate and intensity of antibiotics in pediatric inpatients in Qianxinan People's Hospital from January to December 2021(before intervention)and from January to December 2022(after intervention),and compared the data before and after intervention.Results The utilization rate of antibiotics after intervention was(51.66±2.95)%,which was lower than before intervention(57.01±2.64)%,the difference was significant(P<0.05).After intervention,the intensity of antibacterial drug use(15.63±1.87)DDDs was lower than that before intervention(18.25±1.73)DDDs,and the difference was significant(P<0.05).The incidence of unreasonable prescription of pediatric antibiotics after clinical pharmacist intervention was 3.83%,lower than 2.00%before intervention(P<0.05).The total incidence of adverse reactions to antibiotics after intervention was 0.47%,lower than 0.84%before intervention(P<0.05).After the intervention,the satisfaction of the family members of the affected children with pharmaceutical work was 96.39%,higher than 89.17%before the intervention(P<0.05).Conclusion Clinical pharmacist intervention can improve the level of rational use of pediatric antibiotics,reduce the intensity and utilization rate of drug use,reduce the occurrence of adverse drug reactions,and better ensure the drug safety of children.

Pediatric antibioticsClinical pharmacistInterventionDrug use rateDrug action intensity

王沁

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黔西南州人民医院,贵州兴义 562400

儿科抗菌药物 临床药师 干预 药物使用率 药物使用强度

2024

药品评价
江西省药学会

药品评价

影响因子:0.672
ISSN:1672-2809
年,卷(期):2024.21(6)