Effect of Baogong Zhixue Granules on TCM Syndrome Score and Endometrial Thickness of Patients with Abnormal Uterine Bleeding Due to Ovulation Disorder in Perimenopausal Period
Objective To investigate the effect of baogong zhixue granules on perimenopausal patients with abnormal uterine bleeding due to ovulation disorder(AUB-O).Methods 80 patients with AUB-O admitted to Ganzhou Hospital of Traditional Chinese Medicine from October 2022 to September 2023 were randomly divided into 2 groups with 40 cases each.Hysteroscopic surgery was performed in all patients,and the control group was treated with dydrogesterone tablets,based on this,the observation group was treated with baogong zhixue granules,all for 3 courses of treatment.TCM syndrome score,endometrial thickness(ET),menstruation,hormone level and adverse reactions were compared between the two groups.Results After treatment,the scores of TCM symptoms in two groups decreased,and the observation group was lower(P＜0.05);the scores of menstrual blood loss map(PBAC)and ET were decreased in both groups,and those in observation group were lower(P＜0.05);the levels of prolactin(PRL)and follicular estrogen(FSH)in both groups were decreased,and the observation group was lower;the estradiol(E2)level in both groups was increased,and the observation group was higher(P＜0.05).There was no significant difference in adverse reactions between the two groups(P＞0.05).Conclusion The use of baogong zhixue granules in AUB-O patients can reduce the scores of TCM symptoms,improve menstruation and endometrial conditions,regulate hormone levels,and have high safety.
PerimenopauseAbnormal uterine bleeding due to ovulation disorderBaogong zhixue granulesTCM syndrome score
万方数据
维普
