首页|右美托咪定联合七氟烷吸入麻醉对眼科手术患儿应激反应及苏醒期躁动的影响

右美托咪定联合七氟烷吸入麻醉对眼科手术患儿应激反应及苏醒期躁动的影响

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目的 探讨右美托咪定联合七氟烷吸入麻醉对眼科手术患儿应激反应及苏醒期躁动的影响。方法 以随机数字表法将2021年7月至2023年7月于濮阳市第二人民医院眼科行手术治疗的70例患儿分为两组,各35例。对照组吸入2%七氟醚,基于此观察组加用0。5 μg/kg右美托咪定。比较两组苏醒情况、血流动力学、应激反应以及苏醒期躁动发生情况。结果 两组苏醒时间,麻醉前血流动力学、应激反应指标对比,差异无统计学意义(P>0。05);对照组拔管后血流动力学、应激反应指标均高于麻醉前,且高于观察组,差异有统计学意义(P<0。05)。观察组苏醒期躁动发生率8。57%低于对照组的34。29%,差异有统计学意义(P<0。05)。结论 眼科手术患儿采用右美托咪定联合七氟烷吸入麻醉利于维持血流动力学平稳,减轻应激反应,且不会延长苏醒时间,减少苏醒期躁动发生,值得临床推广应用。
Effects of Dexmedetomidine Combined with Sevoflurane Inhalation Anesthesia on Stress Response and Agitation During Recovery in Children Undergoing Eye Surgery
Objective To investigate the effects of dexmedetomidine combined with sevoflurane inhalation anesthesia on stress response and awakening agitation(EA)in children undergoing eye surgery.Methods A total of 70 children who underwent surgical treatment in The Second People's Hospital of Puyang from July 2021 to July 2023 were divided into 2 groups with 35 cases each.Control group inhaled 2%sevoflurane,based on this observation group plus 0.5μg/kg dexmedetomidine.The recovery,hemodynamics,stress response and EA occurrence were compared between the two groups.Results There were no significant differences in recovery time,pre-anesthesia hemodynamics and stress response indexes between the two groups(P>0.05).The indexes of hemodynamics and stress response after extubation in control group were higher than those before anesthesia,and the difference was statistically significant(P<0.05).The incidence of EA in the observation group was 8.57%lower than that in the control group 34.29%,and the difference was statistically significant(P<0.05).Conclusion The use of dexmedetomidine combined with sevoflurane inhalation anesthesia in children undergoing eye surgery is beneficial to maintain stable hemodynamics,reduce stress response,and does not prolong the recovery time and reduce the occurrence of EA,which is worthy of clinical application.

Eye surgeryDexmedetomidineSevoflurane inhalation anesthesiaStress responseAwakening agitation

赵相中、韩二营、陈金业、孙玉

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濮阳市第二人民医院,河南濮阳 457000

眼科手术 右美托咪定 七氟烷吸入麻醉 应激反应 苏醒期躁动

2024

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江西省药学会

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影响因子:0.672
ISSN:1672-2809
年,卷(期):2024.21(6)