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祛瘀解毒方合常规西药对稳定期COPD症候及肺功能康复情况的影响

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目的 观察祛瘀解毒方联合常规西药对稳定期慢性阻塞性肺疾病(COPD)临床症候及肺功能康复情况的影响。方法 本研究为前瞻性研究,选择项城市中医院2021年1月至2023年1月期间收治的100例稳定期COPD患者为研究对象,采用计算机随机分组法将其分为西医组和中西医组,各50例。西医组实施常规西药治疗,中西医组采用祛瘀解毒方联合常规西药治疗,比较两组患者的临床症候、免疫状态、炎症因子、肺功能改善情况。结果 在不同治疗方案下,中西医组的咳嗽咯痰、胸闷喘息、呼吸困难等症候积分均低于西医组;中西医组的白细胞计数、中性粒细胞数、淋巴细胞计数均低于西医组;中西医组的白细胞介素-6、白细胞介素-8、白细胞介素-10均低于西医组;中西医组的第一秒用力呼气容积、用力肺活量、呼气峰流速均高于西医组;差异均具有统计学意义(P<0。05)。结论 祛瘀解毒方联合常规西药治疗能有效改善稳定期COPD的临床症候,对促进机体免疫状态、炎症反应、肺功能康复均有积极意义。
The Effect of Quyu Jiedu Formula Combined with Conventional Western Medicine on Stable COPD Syndrome and Pulmonary Function Rehabilitation
Objective Observation of the effects of quyu jiedu formula combined with conventional western medicine on the clinical symptoms and pulmonary function recovery of stable chronic obstructive pulmonary disease(COPD).Methods This study was a prospective study,selecting 100 stable COPD patients admitted between January 2021 and January 2023 as the study subjects.They were randomly divided into a western medicine group(50 cases),a traditional Chinese and western medicine group(50 cases)using computer randomization.The western medicine group received conventional western medicine treatment,while the traditional Chinese and western medicine group received conventional western medicine combined with quyu jiedu formula treatment.The clinical symptoms,immune status,inflammatory cells,and lung function improvement of the two groups of patients were compared.Results After treatment,the scores of cough,phlegm,chest tightness,wheezing,and breathing difficulties in the traditional Chinese and western medicine group were lower than the western medicine group;the WBC,NE,and LYM of the traditional Chinese and western medicine group were lower than the western medicine group;the levels of IL-6,IL-8,and IL-10 in the traditional Chinese and western medicine group were lower than the western medicine group;the FVE1,FVC,and PEF of the traditional Chinese and western medicine group were higher than the western medicine group(P<0.05).Conclusion The combination of quyu jiedu formula and conventional western medicine treatment can effectively improve the clinical symptoms of stable COPD,and has a positive significance in promoting the immune status,inflammatory response,and lung function recovery.

Stable chronic obstructive pulmonary diseaseQuyu jiedu formulaClinical symptomsLung function

杨凤玲、聂书慧

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项城市中医院,河南 项城 466200

稳定期慢性阻塞性肺疾病 祛瘀解毒方 临床症候 肺功能

2024

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江西省药学会

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影响因子:0.672
ISSN:1672-2809
年,卷(期):2024.21(6)