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葛根配方颗粒HPLC特征图谱研究

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目的 基于HPLC法建立葛根配方颗粒特征图谱。方法 以HPLC法对自行制备的12批次葛根配方颗粒样本进行测定,并采用《中药色谱指纹图谱相似度评价系统2004A版》软件进行相似度的判断。结果 选择葛根作为特征图谱的参照,同时标定了9个共有峰并指定了其中2个峰,相似度均大于0。99。结论 基于HPLC法建立的葛根配方颗粒特征图谱可用于葛根配方颗粒的质量控制。
Study on HPLC Characteristic Chromatograms of Pueraria Formula Granules
Objective Establish characteristic chromatograms of pueraria formula granules based on HPLC method. Methods The HPLC method was used to determine the similarity of 12 self-prepared batches of pueraria formula granules,and the "SOP of similarity evaluation system for chromatographic fingerprint of TCM (Version 2004 A) " software was used to determine the similarity. Results In the characteristic chromatograms study,pueraria was selected as the reference,and 9 common peaks were calibrated and 2 peaks were specified,with a similarity greater than 0.99. Conclusion The characteristic chromatograms of pueraria formula granules established based on HPLC method can be used for quality control of pueraria formula granules .

PuerariaFormula granulesHPLCCharacteristic chromatograms

廖立英、章顺、付书彬、张文丽

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九江市检验检测认证中心,江西九江332000

葛根 配方颗粒 高效液相色谱法 特征谱图

2024

药品评价
江西省药学会

药品评价

影响因子:0.672
ISSN:1672-2809
年,卷(期):2024.21(8)