药品评价2024,Vol.21Issue(8) :951-954.DOI:10.19939/j.cnki.1672-2809.2024.08.10

葛根配方颗粒HPLC特征图谱研究

Study on HPLC Characteristic Chromatograms of Pueraria Formula Granules

廖立英 章顺 付书彬 张文丽
药品评价2024,Vol.21Issue(8) :951-954.DOI:10.19939/j.cnki.1672-2809.2024.08.10

葛根配方颗粒HPLC特征图谱研究

Study on HPLC Characteristic Chromatograms of Pueraria Formula Granules

廖立英 1章顺 1付书彬 1张文丽1
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作者信息

  • 1. 九江市检验检测认证中心,江西九江332000
  • 折叠

摘要

目的 基于HPLC法建立葛根配方颗粒特征图谱.方法 以HPLC法对自行制备的12批次葛根配方颗粒样本进行测定,并采用《中药色谱指纹图谱相似度评价系统2004A版》软件进行相似度的判断.结果 选择葛根作为特征图谱的参照,同时标定了9个共有峰并指定了其中2个峰,相似度均大于0.99.结论 基于HPLC法建立的葛根配方颗粒特征图谱可用于葛根配方颗粒的质量控制.

Abstract

Objective Establish characteristic chromatograms of pueraria formula granules based on HPLC method. Methods The HPLC method was used to determine the similarity of 12 self-prepared batches of pueraria formula granules,and the "SOP of similarity evaluation system for chromatographic fingerprint of TCM (Version 2004 A) " software was used to determine the similarity. Results In the characteristic chromatograms study,pueraria was selected as the reference,and 9 common peaks were calibrated and 2 peaks were specified,with a similarity greater than 0.99. Conclusion The characteristic chromatograms of pueraria formula granules established based on HPLC method can be used for quality control of pueraria formula granules .

关键词

葛根/配方颗粒/高效液相色谱法/特征谱图

Key words

Pueraria/Formula granules/HPLC/Characteristic chromatograms

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出版年

2024
药品评价
江西省药学会

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影响因子:0.672
ISSN:1672-2809
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