首页|健胃舒颗粒联用艾司奥美拉唑治疗慢性非萎缩性胃炎成本-效果分析

健胃舒颗粒联用艾司奥美拉唑治疗慢性非萎缩性胃炎成本-效果分析

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目的 通过对比分析健胃舒颗粒联用艾司奥美拉唑和单用艾司奥美拉唑、单用健胃舒颗粒治疗慢性非萎缩性胃炎的成本-效果,研究健胃舒颗粒在治疗方案中的作用和意义.方法 开展随机分组临床试验,根据慢性非萎缩性胃炎的中西医诊断标准观察三种给药方案干预下患者疾病及症状的改善情况,对所得结果进行量化评分.同时收集各组用药经济成本数据,进行适当转化处理后与疗效量化评估结果进行数据分析,得出各组成本-效果参数,进而分析并判断三种诊疗方案谁为最优.结果 在治愈率上,健胃舒颗粒联用艾司奥美拉唑的治愈率最高;从成本-效果参数出发,健胃舒颗粒联用艾司奥美拉唑的成本-效果比,增量成本-效果比也均为三种方案中最佳,平均治愈用药费用与单用艾司奥美拉唑差异无统计学意义(P>0.05),但明显优于单用健胃舒颗粒(P<0.05).结论 本研究通过组合对比分析,证实健胃舒颗粒联用艾司奥美拉唑的总体成本-效果最优.
Cost-effectiveness Analysis of Jianweishu Granules Combined with Esomeprazole in the Treatment of Chronic Non-atrophic Gastritis
Objective To compare and analyze the cost-effectiveness of jianweishu granules combined with esomeprazole and esomeprazole alone or jianweishu granules alone in the treatment of chronic non-atrophic gastritis,and to study the role and significance of jianweishu granules in the treatment. Methods A randomized clinical trial was conducted to observe the improvement of the disease and symptoms of patients with chronic non-atrophic gastritis under the intervention of three drug administration schemes according to the diagnostic criteria of traditional Chinese and Western medicine,and the results were quantitatively scored. At the same time,the economic cost data of medication for patients in each experimental group were collected,and the data were analyzed after proper transformation processing and the results of quantitative evaluation of efficacy. Cost-effectiveness parameters of each group were obtained,and then the cost-effectiveness parameters of the three treatment schemes were analyzed and judged as the best. Results According to the cost-effectiveness parameters,the average improvement cost,cost-effectiveness ratio and incremental cost-effectiveness ratio of jianweishu granules combined with esomeprazole were the best among the three regimens. Respectively,there was no significant difference in the average treatment cost between jianweishu granules combined with esomeprazole alone (P>0.05),but it was significantly better than jianweishu granules alone (P<0.05). Conclusion In this study,the overall cost-effectiveness of jianweishu granules combined with esomeprazole was proved to be the best.

Jianweishu granulesEsomeprazoleCost-effectiveness analysisChronic non-atrophic gastritis

洪笃云、程良凯、董玉娟、欧阳炜、麦炳明

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广东省第二中医院(广东省中医药工程技术研究院),广东广州 510095

健胃舒颗粒 艾司奥美拉唑 成本-效果分析 慢性非萎缩性胃炎

2024

药品评价
江西省药学会

药品评价

影响因子:0.672
ISSN:1672-2809
年,卷(期):2024.21(8)