同位素内标-三重四极杆气相色谱-质谱法测定纺织品中的丙烯酰胺

Determination of acrylamide in textiles using isotope internal standard method by gas chromatography-triple quadrupole mass spectrometry

毛世南 ¹董冰夏 ¹李梦洁 ¹孙静 ¹严方平 ¹章伊楠 ¹王晓晴 ¹王玲霞¹

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作者信息

1. 浙江省质量科学研究院,浙江杭州 310000
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摘要

建立了用三重四极杆气相色谱-质谱联用仪快速测定纺织品中丙烯酰胺的方法.样品中加入 13C3-丙烯酰胺同位素内标,以乙醇作为萃取溶剂,超声萃取纺织品中丙烯酰胺,萃取液经过滤直接进样,用多反应监测模式(MRM)进行定性及定量分析.结果表明,丙烯酰胺在0.005～20.000 mg/L的质量浓度范围内方法线性良好,相关系数R2达0.999 2,阴性样品在三个质量浓度水平的加标平均回收率为90.0%～109.3%,相对标准偏差(n=6)为1.6%～2.1%,方法的定量限为0.025 mg/kg,可满足纺织品中丙烯酰胺的测定.

Abstract

A method for the determination of acrylamide in textiles using isotope internal standard method by gas chromatography-triple quadrupole mass spectrometry(GC-MS/MS)is developed.Isotopic internal stan-dard of acrylamide is added into the samples,then ethanol is used as the extraction agent for ultrasonic extrac-tion.The extracts are analyzed by GC-MS/MS using multiple reaction monitoring(MRM)mode.The results show that acrylamide has good linear relationship(R2=0.999 2)in the range of 0.005-20.000 mg/L.The recover-ies are in the range of 90.0%-109.3%,and the relative standard deviations(n=6)are in the range of 1.6%-2.1%.The limit of quantity is 0.025 mg/kg,which can meet the determination requirements of acrylamide in textiles.

关键词

测试/同位素内标/三重四极杆气相色谱-质谱法/丙烯酰胺/纺织品

Key words

testing/isotope internal standard/gas chromatography-triple quadrupole mass spectrometry/acryl-amide/textiles

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出版年

2025

印染

上海市纺织科学研究院全国印染科技信息中心

印染

北大核心

影响因子：0.705

ISSN：1000-4017

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