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低浓度阿托品在儿童近视控制中的研究进展

Research Progress of Low-Concentration Atropine for Myopia Control in Children

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伴随着儿童近视发生率的上升和低龄化趋势,近视已成为亟需解决的全球公共卫生问题。控制近视发生发展的有效措施包括双焦眼镜、多焦眼镜、角膜塑形镜和药物等。近年来,阿托品作为控制近视发展的有效药物得到广泛关注。由于低浓度阿托品可以有效控制近视屈光度和眼轴增长,且畏光、视近模糊等不良反应轻,故低浓度阿托品已成为儿童近视防控的研究重点。现就低浓度阿托品在儿童近视控制中的研究进展进行综述。 With the increasing incidence of myopia in children and a younger age of myopia onset, myopia has become a global public health problem, which needs to be addressed immediately. Effective interventions for myopia control include bifocal glasses, multi-focal glasses, orthokeratology lens and pharmacologic, etc. Recently, atropine eye drops have obtained widespread concern for its effectiveness in suppressing the myopia progression. As low-dose atropine can effectively control myopia progression and axial growth, with significantly less adverse events such as photophobia and blurred near vision compared to higher concentration preparation, low-concentration atropine has become one of the important research areas for myopia prevention and control in children. This article summarizes the research progress of low-concentration atropine in myopia control of children.
With the increasing incidence of myopia in children and a younger age of myopia onset, myopia has become a global public health problem, which needs to be addressed immediately. Effective interventions for myopia control include bifocal glasses, multi-focal glasses, orthokeratology lens and pharmacologic, etc. Recently, atropine eye drops have obtained widespread concern for its effectiveness in suppressing the myopia progression. As low-dose atropine can effectively control myopia progression and axial growth, with significantly less adverse events such as photophobia and blurred near vision compared to higher concentration preparation, low-concentration atropine has become one of the important research areas for myopia prevention and control in children. This article summarizes the research progress of low-concentration atropine in myopia control of children.

atropinemyopiaclinical trialsadverse events

杨璐绫、吕会斌、陈跃国、李学民、季魏红

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北京大学第三医院眼科,北京 100191

阿托品 近视 临床研究 不良反应

2022

中华眼视光学与视觉科学杂志
中华医学会

中华眼视光学与视觉科学杂志

CSTPCDCSCD
影响因子:0.783
ISSN:1674-845X
年,卷(期):2022.24(12)
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