Objective:To investigate the medication patterns of Traditional Chinese Medicine(TCM)in treating alopecia through data mining of ancient Chinese medical texts,and to explore hospital preparation formulations for alopecia treatment in conjunction with modern TCM pharmaceutical technology.Methods:Prescriptions for alopecia treatment were selected from the Chinese Medical Code based on inclusion and exclusion criteria.The"Ancient and Modern Medical Cases Cloud Platform"was used to analyze drug frequency,TCM properties(four natures,five fla-vors,nature and flavor,meridian tropism),association rules,and cluster analysis.Based on the data analysis results and traditional preparation technology requirements,preliminary hospital preparation prescriptions for alopecia treatment were formulated.Results:38 oral prescriptions and 84 external use prescriptions were included.The majority of herbs were warm or slightly warm in nature,with sweet and pungent flavors,primarily entering the liver,kidney,and spleen meridians.Oral preparations mainly functioned to moisten the intestines,promote bowel movement,strengthen the body,and detoxify.External preparations primarily acted to promote qi circulation,dispel wind,release the exterior,and disperse cold.Cluster analysis yielded two basic formulas each for oral and external use.Combining modern hospital preparation requirements and medication characteristics,three new hospital preparation formulas were preliminarily de-veloped.Conclusion:The medication patterns of alopecia treatment prescriptions applied to hospital preparation formu-lations align with fundamental TCM theory and conform to modern therapeutic concepts for alopecia treatment.
关键词
脱发/《中华医典》/古今医案云平台/用药规律/制剂组方
Key words
Alopecia/Chinese Medical Code/Ancient and Modern Medical Case Cloud Platform/Law of Drug Use/Prep-aration Formulation