首页|基于表观遗传修饰探究中医药防治抑郁症认知障碍研究进展

基于表观遗传修饰探究中医药防治抑郁症认知障碍研究进展

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抑郁症是全球发病率最高的精神疾病之一,认知障碍可发生在抑郁症病程的任何一个阶段。大量研究表明抑郁症认知障碍的发病机制大多以海马突触可塑性损伤和神经再生障碍为基础。基于中医学与表观遗传学的相关性,通过对近年来中医药干预疗法调控表观遗传修饰改善抑郁症认知障碍的相关文献进行分析总结,以期为防治抑郁症认知障碍提供新视角。
Research Progress of Traditional Chinese Medicine Prevention and Treatment of Cognitive Impairment in Depression Based on Epigenetic Modification
Depression is one of the most common mental diseases in the world,and cognitive impairment can occur at any stage of the course of depression.A large number of studies have shown that the pathogenesis of cognitive impair-ment in depression is mostly based on the damage of hippocampal synaptic plasticity and nerve regeneration disorders.Based on the correlation between traditional Chinese medicine(TCM)and epigenetics,this paper analyzed and summa-rized the relevant literature on the improvement of cognitive impairment in depression by TCM intervention therapy in recent years,in order to provide a new perspective for the prevention and treatment of cognitive impairment in depres-sion.

Traditional Chinese MedicineEpigenetic ModificationDepressionCognitive ImpairmentResearch Progress

林珊珊、陈雅茹、刘依婷、林泓睿、杨鹤鑫、林玥、谢丽霞、沈建英

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福建中医药大学,福建 福州 350122

中医药 表观遗传修饰 抑郁症 认知障碍 研究进展

2025

亚太传统医药
中国民族医药学会 湖北省科技信息研究院

亚太传统医药

影响因子:0.743
ISSN:1673-2197
年,卷(期):2025.21(1)