Depression is one of the most common mental diseases in the world,and cognitive impairment can occur at any stage of the course of depression.A large number of studies have shown that the pathogenesis of cognitive impair-ment in depression is mostly based on the damage of hippocampal synaptic plasticity and nerve regeneration disorders.Based on the correlation between traditional Chinese medicine(TCM)and epigenetics,this paper analyzed and summa-rized the relevant literature on the improvement of cognitive impairment in depression by TCM intervention therapy in recent years,in order to provide a new perspective for the prevention and treatment of cognitive impairment in depres-sion.
关键词
中医药/表观遗传修饰/抑郁症/认知障碍/研究进展
Key words
Traditional Chinese Medicine/Epigenetic Modification/Depression/Cognitive Impairment/Research Progress