尿微量白蛋白检测对妊娠期高血压患者早期肾损伤的诊断价值分析
Analysis of the Diagnostic Value of Urinary Microalbumin Test for Early Kidney Injury in Hypertensive Patients during Pregnancy
程军 1骆文龙1
作者信息
- 1. 安徽省铜陵市妇幼保健院,安徽铜陵 244000
- 折叠
摘要
本研究旨在探讨尿微量白蛋白检测在妊娠期高血压患者早期肾损伤诊断中的应用价值,以期为早期肾损伤的临床诊断和干预提供更科学的依据.选取2022年1月至2023年6月于本院就诊的妊娠期高血压患者150例为研究对象,所有孕妇均进行尿微量白蛋白和血清肌酐水平检测,并记录临床特征和孕妇结局.同时,比较尿微量白蛋白与其他肾功能指标的相关性.在150例妊娠期高血压患者中,尿微量白蛋白检测呈阳性的有95例(63.3％),提示早期肾损伤.尿微量白蛋白阳性组患者的肌酐水平、平均收缩压、舒张压及尿蛋白定量显著高于阴性组(P＜0.05).尿微量白蛋白检测结果与收缩压之间存在中度正相关关系(r=0.421,P＜0.01),即随着尿微量白蛋白检测结果的增加,收缩压呈现增加的趋势.尿微量白蛋白检测结果与舒张压之间存在轻度正相关关系(r=0.315,P＜0.01),即尿微量白蛋白检测结果升高可能伴随舒张压的轻度增加.尿微量白蛋白检测结果与早产发生率之间存在中度正相关关系(r=0.529,P＜0.01),即尿微量白蛋白检测结果的升高与早产发生率的增加相关.此外,阳性组患者更容易出现早产等并发症(P＜0.01).尿微量白蛋白检测在妊娠期高血压患者早期肾损伤的诊断中具有较好的应用价值,阳性结果可能提示患者存在肾损伤的风险,需要密切监测和干预,以降低不良孕妇及胎儿结局的发生率.
Abstract
This study aims to explore the application value of urine microalbumin detection in the early diagnosis of renal damage in patients with pregnancy-induced hypertension,providing a more scientific basis for the clinical diagnosis and intervention of early renal damage.A total of 150 patients with pregnancy-induced hypertension who visited the authors'hospital from January 2022 to June 2023 were selected as the research subjects.All pregnant women underwent urine microalbumin and serum creatinine level tes-ting,and clinical characteristics and maternal outcomes were recorded.The correlation between urine microalbumin and other renal function indicators was also compared.Among the 150 patients with pregnancy-induced hypertension,95 cases(63.3％)showed positive results in urine microalbumin detection,suggesting early renal damage.Patients in the urine microalbumin-positive group had significantly higher levels of creatinine,average systolic blood pressure,diastolic blood pressure,and quantitative urine protein than the negative group(P＜0.05).The results of urine microalbumin detection showed a moderate positive correlation with systolic blood pressure(r=0.421,P＜0.01),indicating an increasing trend in systolic blood pressure with the rise in urine microalbumin detection results.There was a mild positive correlation between urine microalbumin detection results and diastolic blood pressure(r=0.315,P＜0.01),suggesting a slight increase in diastolic blood pressure with higher urine microalbumin detection results.Fur-thermore,there was a moderate positive correlation between urine microalbumin detection results and the rate of premature delivery(r=0.529,P＜0.01),implying an association between elevated urine microalbumin detection results and an increased incidence of premature delivery.Furthermore,patients in the positive group were more likely to experience complications such as premature delivery(P＜0.01).Urine microalbumin detection has good application value in the early diagnosis of renal damage in patients with pregnancy-induced hypertension.A positive result may indicate a risk of renal damage in patients,necessitating close monitoring and intervention to reduce the occurrence of adverse maternal and fetal outcomes.
关键词
妊娠期高血压/尿微量白蛋白/早期肾损伤/诊断价值/孕妇健康/早产Key words
Gestational hypertension/Urinary microalbumin/Early renal damage/Diagnostic value/Maternal health/Premature delivery引用本文复制引用
出版年
2024
NETL
NSTL
万方数据