Research Progress on Immunoregulation of Chemotherapeutic Agents
The report of Global Cancer Statistics 2020 showed that cancer had become the No.1 cause of death in China.Exploring novel cancer therapeutic strategies has been a hot research topic among scientists.Currently,chemotherapy is still one of the most common treatments for cancer in clinical,with strong lethal effects on tumor cells but toxic side effects on somatic tissues.Further studies have elucidated that chemotherapeutic drugs also play a specific immunomodulatory role in cancer treatment in addition to tu-moricidal effects.This review introduces the classification and characteristics of chemotherapeutic drugs,describes their immune sup-pressive mechanisms and immune potentiating functions,and summarizes their applications in cancer immunotherapy to provide new insights into the application of chemotherapeutic drugs in cancer immunotherapy.
NETL
NSTL
万方数据
