Research Progress in the Field of CAR-T Cell Therapy for Tumor Treat-ment
In recent years,chimeric antigen receptor T-cell(CAR-T)therapy has achieved significant success in the field of oncology.This treatment involves genetically modifying T cells ex vivo to express a chimeric antigen receptor,which allows for the targeted expansion and subsequent infusion into the patient's body to specifically recognize and eliminate tumor cells.Although CAR-T therapy has demonstrated remarkable efficacy in hematological malignancies,its effectiveness in solid tumors has been less satisfactory.This article primarily consolidates the latest advancements in CAR-T cell therapy,both domestically and internationally,including developments in the treatment of hematological and solid tumors,as well as the integration of new technologies with CAR-T therapy.It provides an overview of the work conducted to enhance the therapeutic outcomes of CAR-T treatments.
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