Diagnostic Value of New Combined Detection in Neonatal Infectious Diseases
To analyze the diagnostic value of non-specific early inflammatory markers in neonatal infectious diseases,this study con-structed a retrospective case-control analysis,167 patients in the neonatal ward of the hospital were divided into infection group and non-infection group.There were 71 naonates in the infection group and 96 naonates in non-infectious group.The data of the first labo-ratory examination on admission or untreated were analyzed in both groups,the sensitivity,the specificity and the ROC curve of pro-calcitonin(PCT),C-reactive protein(CRP),serum amyloid protein(SAA)and peripheral blood white blood cell count(WBC)were compared between the two groups.The diagnostic efficacy of each index in neonatal infectious diseases was analyzed.The test group and the control group were compared with each index result.The single detection of the above indicators in the two groups is not significant as an early inflammation indicator,but combined detection has certain significance.The sensitivity of PCT,CRP,SAA,traditional combined detection and new combined detection were 16.9％,11.3％,14.1％,15.5％,29.6％and 36.6％respectively.The specificity were 97.9％,97.9％,96.9％,85.5％,86.5％and 85.4％respectively.The area under the ROC curve were 0.574,0.546,0.555,0.52,0.58 and 0.61 respectively.The diagnostic value of single non-specific early inflammatory markers is not strong,and the combined detection is more significant.And it may be helpful for the early diagnosis and treatment of neonatal infectious diseases to properly introduce more non-specific indicators with high diagnostic potency for combined detection.Especially,serum amyloid protein is a new indicator that is efficient and economical,adding it to joint testing may help in the early diagnosis and treatment of neonatal infectious diseases.
Non-specific early inflammatory markersNeonatal infectionDiagnostic potencyThe combined detectionSensitivitySpecificityReceiver operating curveSerum amyloid protein
NETL
NSTL
万方数据
