Progress of Difelikefalin in the Treatment of Hemodialysis Pruritus
One of the common complications of hemodialysis patients was pruritus,not only affected the physical and mental health of the patients and increased the risk of mortality,but also imposed a significant burden on patients'families,healthcare providers,and society.Various hypotheses regarding the pathogenesis of pruritus existed,but the jury was still out.There was also a lack of targeted strategies for the treatment of this complication.The physiological mechanism and progress of difelikefalinof FDA recently approved the drug in the treatment of hemodialysis-related pruritus were reviewed in this article.
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