CT与MRI对视网膜母细胞瘤及其视神经侵犯的诊断价值比较
Comparison of the value of CT and MRI in diagnosing retinoblastoma and its optic nerve invasion
高贯金 1郭大立 1魏少峰1
作者信息
- 1. 濮阳市第二人民医院医学影像科 濮阳市眼科医院,濮阳 457000
- 折叠
摘要
目的 比较计算机断层扫描(CT)和磁共振成像(MRI)对视网膜母细胞瘤(RB)及其视神经侵犯的诊断价值.方法 前瞻性队列研究.纳入濮阳市第二人民医院 2021 年 1 月至 2024 年 1月共 63 例疑诊为RB的患者同时行CT和MRI检查,以病理检查结果为"金标准",比较CT与MRI诊断RB的敏感度及RB视神经侵犯分期符合率.采用Kappa检验分析两种检查的一致性.结果 病理诊断显示RB 44 例,非RB 19 例;CT诊断RB的敏感度为 93.18%(41/44),特异度为 89.47%(17/19),准确度为 92.06%(58/63),Kappa值为 0.81;MRI诊断RB的敏感度为 75.00%(33/44),特异度为 84.21%(16/19),准确度为 77.78%(49/63),Kappa值为 0.53;CT诊断RB的敏感度、准确率显著高于MRI(χ2=5.44、5.02,P=0.020、0.025),CT与MRI诊断RB特异度比较差异无统计学意义(P=1.000);MRI诊断RB视神经侵犯分期符合率84.85%(28/33),明显高于CT的 63.41%(26/41)(χ2=4.26,P=0.039).结论 CT诊断RB准确率较高,但MRI在评估RB视神经侵犯方面具有较大优势.
Abstract
Objective To compare the value of computed tomography(CT)and magnetic resonance imaging(MRI)in the diagmosis of retinoblastoma(RB)and its optic nerve invasion.Methods A total of 63 patients of suspected RB were simultaneously examined with CT and MRI before surgery in the Second People's Hospital of Puyang from Jan.2021 to Jan.2024 in this prospective cohort study.Pathological examination was used as the gold standard to compare the sensitivity of CT and MRI in diagnosing RB as well as the accordance rate in the staging of RB optic nerve invasion.The consistency of the two methods were analyzed using the Kappa test.Results Pathological diagnosis showed 44 cases with RB and 19 cases without RB.The sensitivity,specificity,accuracy and Kappa value of CT for diagnosing RB were 93.18%(41/44),89.47%(17/19),92.06%(58/63)and 0.81,respectively.The sensitivity,specificity,accuracy and Kappa value of MRI for diagnosing RB were 75.00%(33/44),84.21%(16/19),77.78%(49/63)and 0.53,respectively.The sensitivity and accuracy of CT for diagnosing RB were significantly higher than those of MRI(χ2=5.44,5.02;P=0.020,0.025),but the difference in specificity showed no statistical significance(P=1.000).The accordance rate of MRI for diagnosing the stage of RB optic nerve invasion was 84.85%(28/33),which was significantly higher than that of CT[63.41%(26/41)](χ2=4.26,P=0.039).Conclusion CT has relatively higher accuracy in diagnosing RB,but MRI has more advantages in evaluating RB optic nerve invasion.
关键词
视网膜母细胞瘤/计算机断层扫描/磁共振成像/侵犯/视神经Key words
Retinoblastoma/X-ray computed tomography/Magnetic resonance imaging/Invasion/Optic nerve引用本文复制引用
出版年
2024
NETL
NSTL
万方数据